Reoperation for Severe Pancreatitis

Severe Acute Pancreatitis and Necrotizing Pancreatitis.

Acute pancreatitis results in nearly 250,000 admissions annually. Acute pancreatitis varies widely in its clinical presentation. Pancreatic necrosis accounts for substantial additional morbidity, with mortality rates remaining as high as 10% to 20% despite advances in critical care. The extent of necrosis correlates well with the incidence of infected necrosis, multiorgan failure, need for panc...

Severe acute pancreatitis

Pancreatitis is an inflammatory disorder of the pancreas which occurs with an estimated incidence of 10–40 per 100 000 per year in the UK. Mild acute (oedematous or interstitial) pancreatitis accounts for 80% of cases, is self-limiting, and usually resolves with simple supportive management in 3–5 days. Severe acute pancreatitis (SAP) accounts for the remainder of cases and was defined by the A...

Severe Acute Pancreatitis

Methods Between April 22, 1990 and April 19, 1993, 102 patients with severe acute pancreatitis were admitted to 16 participating hospitals. Patients were entered into the study if severe acute pancreatitis was indicated, on admission, by multiple laboratory criteria (Imrie score 2 3) and/or computed tomography criteria (Balthazar grade D or E). Patients were randomly assigned to receive standar...

Severe acute pancreatitis.

Pterostilbene as treatment for severe acute pancreatitis.

Acute pancreatitis (AP) has a fast onset and progression, which lead to an unfavorable prognosis. Therefore, the development of novel drugs for its treatment is critical. As a homologous derivative of resveratrol, pterostilbene exerts a variety of effects including anti-inflammatory, antioxidant, and antitumor effects. This study investigated the potential of pterostilbene for treatment of seve...